Mexican RestaurantFrederick, MD

Cafe Rio – Frederick, MD

Open now · closes 10:00 PM

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Illustrative photo

Opening hours

Open now · closes 10:00 PM

Weekly opening hours of Cafe Rio
Monday	10:30 AM – 10:00 PM
Tuesday	10:30 AM – 10:00 PM
Wednesday	10:30 AM – 10:00 PM
Thursday	10:30 AM – 10:00 PM
Friday	10:30 AM – 10:00 PM
Saturday	10:30 AM – 10:00 PM
Sunday	11:00 AM – 10:00 PM

Local time in Frederick: 5:00 PM (EDT). Holiday hours may differ – call (240) 415-7240 to confirm.

Location & directions

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5100 Buckeystown Pike
Frederick, MD 21704

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About Cafe Rio

Looking for a Mexican restaurant in Frederick? Cafe Rio is at 5100 Buckeystown Pike, Frederick, Maryland. It is one of 204 places to eat and drink we list in Frederick.

Cafe Rio is open 7 days a week, usually 10:30 AM – 10:00 PM.

You can visit for dine-in.

Phone: (240) 415-7240.

Quick facts

Category: Mexican Restaurant
Address: 5100 Buckeystown Pike, Frederick, MD 21704
Phone: (240) 415-7240
Hours: Open 7 days a week, usually 10:30 AM – 10:00 PM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for Mexican restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Dine-in

Reviews

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Frequently asked questions

What are Cafe Rio's opening hours?

Open 7 days a week, usually 10:30 AM – 10:00 PM. Monday: 10:30 AM – 10:00 PM; Tuesday: 10:30 AM – 10:00 PM; Wednesday: 10:30 AM – 10:00 PM; Thursday: 10:30 AM – 10:00 PM; Friday: 10:30 AM – 10:00 PM; Saturday: 10:30 AM – 10:00 PM; Sunday: 11:00 AM – 10:00 PM.

Is Cafe Rio open on Sunday?

Yes, Cafe Rio is open on Sundays: 11:00 AM – 10:00 PM.

Where is Cafe Rio located?

Cafe Rio is located at 5100 Buckeystown Pike, Frederick, MD 21704.

What is the phone number of Cafe Rio?

You can call Cafe Rio at (240) 415-7240.

Does Cafe Rio offer delivery or takeout?

Delivery is not listed for Cafe Rio. Listed service options: dine-in.